Acidex Advance Oral Suspension Aniseed Flavour 200mg/1000mg – 500ml

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What Is Acidex Advance Oral Suspension Aniseed Flavour Used For?
Heartburn, acid reflux, and indigestion are everyday realities for a significant proportion of people across the UK. The familiar burning sensation rising from the stomach into the chest and throat, the sour taste of acid coming back up, and the discomfort of indigestion after meals can all disrupt eating, sleep, and general wellbeing. Acidex Advance Oral Suspension Aniseed Flavour is an alginate-based antacid suspension designed to help relieve these symptoms by creating a physical protective raft in the stomach that helps prevent acid from refluxing into the oesophagus. The 500ml bottle is an economy-sized format of the same proven formulation, offering excellent value for those who use the product regularly or wish to keep a supply at home without frequent repurchasing.
Acidex Advance works through a dual-action approach that sets it apart from simple antacid preparations. When the suspension reaches the stomach, sodium alginate reacts with natural stomach acid to form a thick, cohesive gel. Sodium bicarbonate simultaneously generates carbon dioxide, which makes this gel buoyant, causing it to rise and float on the surface of the stomach contents as a physical raft. This raft acts as a mechanical barrier, helping to physically prevent stomach acid and contents from refluxing upward into the oesophagus. Calcium carbonate provides additional antacid activity by directly neutralising excess stomach acid and helping to reinforce the structural integrity of the raft. Together, these three active ingredients address both the mechanical trigger of reflux and the chemical irritation it causes.
The 500ml suspension format is particularly practical for those who experience reflux regularly and prefer to dose after each meal and at bedtime as directed, as well as for households where more than one person uses the product. The aniseed flavour makes it a pleasant and palatable preparation to take, and the liquid format is especially useful for those who find tablets or capsules difficult to swallow. The bottle should always be shaken well before each dose and stored below 25°C. Please note that, as with all opened oral liquid preparations, the bottle should be discarded 28 days after first opening, regardless of how much product remains.
Acidex Advance is suitable for adults and young people aged 12 and over. It is not recommended for children under 6 and caution is advised in children aged 6 to 11. Those on sodium-restricted diets, with kidney impairment, or taking other medicines should seek pharmacist advice before use. If your symptoms are severe, worsening, or persistent beyond one week, or are accompanied by difficulty swallowing, unexplained weight loss, or vomiting, seek prompt assessment from your GP. Speak to a Pearl Chemist Group pharmacist for guidance on whether this product is right for you, or browse our full heartburn and indigestion range for further options.
How to Use Acidex Advance Oral Suspension Aniseed Flavour 500ml
- Shake the bottle well before every dose. The active ingredients can settle in the bottle between uses. Shake thoroughly each time before measuring to ensure an accurate, consistent dose.
- Measure your dose accurately. Use a 5ml medicine measuring spoon or an oral dosing syringe. Do not estimate using a household teaspoon, which may not hold exactly 5ml and could result in under or over-dosing.
- Take after meals and at bedtime. For the raft to form effectively, there should be stomach contents for it to float on. Always take after eating rather than before meals or on an empty stomach.
- Swallow directly. Take the measured dose by mouth without mixing with water or other drinks, as dilution may reduce the effectiveness of the raft-forming mechanism.
- Remain upright after post-meal doses where possible. Staying upright for at least 20 to 30 minutes after a dose helps the raft to position itself optimally. The bedtime dose can be taken before lying down.
- Replace the cap and store correctly. Replace the cap firmly after every use. Write the date of opening on the label and keep the bottle stored below 25°C.
Practical tips for the 500ml pack
- Write the opening date on the bottle label immediately. Despite the larger size, the bottle must be discarded 28 days after opening to maintain safety and efficacy.
- If multiple members of a household are using the product, consider noting each person's opening date separately if a second bottle is opened at a different time.
- Take any other medicines at least 2 hours before or after a dose of Acidex Advance to minimise the risk of interaction.
Acidex Advance Oral Suspension Aniseed Flavour 500ml Side Effects
Acidex Advance Oral Suspension is generally well tolerated when used as directed. Side effects are uncommon.
Common side effects (may affect more than 1 in 10 people)
- Increased wind or bloating as a result of the carbon dioxide generated during raft formation — this is a normal consequence of how the product works and is usually mild and temporary
Less common side effects (may affect between 1 in 10 and 1 in 100 people)
- Nausea or an unpleasant taste, particularly if taken in large quantities
- Constipation, associated with the calcium carbonate component
- Diarrhoea in some individuals
- Mild stomach discomfort or cramping
Rare side effects (may affect fewer than 1 in 100 people)
- Allergic reaction to one or more ingredients, including parabens, presenting as skin rash, itching, or swelling
- Electrolyte imbalance with excessive or prolonged use in those with kidney impairment
Stop using and seek medical help if you experience:
- A serious allergic reaction including significant facial or throat swelling, difficulty breathing, or a widespread rash — call 999 immediately
- Severe or worsening abdominal pain
- Any symptom that concerns you or that you believe may be related to this product
Report any unexpected reaction via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk or speak to your Pearl Chemist Group pharmacist.
How to Store Acidex Advance Oral Suspension Aniseed Flavour 500ml
- Temperature: Store below 25°C. Keep away from direct sunlight and sources of heat.
- Do not refrigerate.
- After opening: Discard 28 days after first opening regardless of how much product remains in the 500ml bottle. Write the date of opening on the label immediately.
- Before each use: Shake well before measuring each dose.
- Cap: Replace the cap firmly after every use.
- Children: Keep out of the sight and reach of children at all times.
- Expiry: Do not use after the expiry date printed on the bottle and outer packaging.
- Disposal: Do not dispose of via wastewater or household waste. Ask your Pearl Chemist Group pharmacist about safe disposal.
Who Is Acidex Advance Oral Suspension Aniseed Flavour 500ml Suitable For?
Acidex Advance Oral Suspension Aniseed Flavour 500ml is suitable for adults and young people aged 12 and over who experience symptoms of gastro-oesophageal reflux, including heartburn, acid regurgitation, and indigestion, and who prefer or require an economy-sized liquid format for regular or household use.
Suitable for:
- Adults aged 18 and over experiencing heartburn, acid reflux, or indigestion after meals or at night
- Young people aged 12 to 17, subject to appropriate adult supervision
- Those who use the product regularly and prefer an economy pack size to reduce the frequency of repurchasing
- Households where more than one person uses the product
- Those who prefer a liquid suspension over tablets or capsules, including people who find swallowing tablets difficult
- People who find alginate-based raft-forming preparations more effective for their reflux than simple antacids
- Those who experience nocturnal reflux or symptoms that disturb sleep
Not suitable for:
- Children under 6 years of age
- Children aged 6 to 11 years, unless specifically directed by a doctor
- Anyone with a known allergy or hypersensitivity to sodium alginate, sodium bicarbonate, calcium carbonate, parabens (E216/E218), or any other ingredient
Use with caution or seek advice first if you:
- Are on a sodium-restricted diet, as each dose contains a significant amount of sodium
- Have impaired kidney function
- Are taking any other prescribed or over-the-counter medicines
- Are pregnant or breastfeeding
- Have symptoms that are severe, persistent beyond 7 days, or accompanied by difficulty swallowing, weight loss, or vomiting
Our Pearl Chemist Group pharmacists are always available to help you confirm whether this product is appropriate for your symptoms and circumstances.
Active Ingredients in Acidex Advance Oral Suspension Aniseed Flavour 500ml
| Ingredient | Strength per 5ml dose | Role |
|---|---|---|
| Sodium alginate | 200mg | The primary active and raft-forming ingredient. Derived from brown seaweed, sodium alginate reacts with stomach acid to form a thick, cohesive gel that floats on the stomach contents as a physical raft, helping to mechanically prevent acid from refluxing up into the oesophagus. |
| Sodium bicarbonate | 133.5mg | Reacts with stomach acid to release carbon dioxide, making the alginate gel buoyant so that it floats effectively on the stomach contents. Also provides mild direct antacid activity by neutralising excess stomach acid. |
| Calcium carbonate | 80mg | Provides additional antacid activity by neutralising excess stomach acid directly. Also helps to reinforce and stabilise the physical structure of the alginate raft. |
Acidex Advance Oral Suspension Aniseed Flavour 500ml Dosage — How Much to Take
Adults and young people aged 12 and over
- Dose: 10–20ml (2 to 4 x 5ml spoonfuls) per dose.
- When to take: After meals and at bedtime.
- Maximum daily dose: 4 doses in any 24-hour period (maximum 80ml per day).
- How to take: Shake the bottle well before each use. Measure using a 5ml medicine spoon or oral syringe. Take orally after food.
Children aged 6 to 11 years
5–10ml after meals and at bedtime, under direct medical supervision only.
Children under 6 years
Not recommended.
Elderly patients
No specific dose adjustment required. Use the standard adult dose with caution if kidney function is impaired — seek pharmacist or GP guidance first.
Important dosage notes
- Do not exceed 4 doses in 24 hours.
- Always shake the bottle thoroughly before each dose.
- Do not use continuously for more than 7 days without consulting a pharmacist or GP.
- Discard the bottle 28 days after opening, even for a 500ml pack where product remains.
Precautions When Using Acidex Advance Oral Suspension Aniseed Flavour 500ml
Before you use this product
- Check the expiry date on the bottle and outer packaging.
- Check that the bottle seal is intact before first opening.
- Review drug interactions and consult your pharmacist if you take any regular medicines.
- If on a sodium-restricted diet or with kidney disease, seek pharmacist or GP advice before use.
During use
- Shake well before every dose.
- Measure accurately using a 5ml spoon or oral syringe.
- Do not mix with other drinks before taking.
- Take other medicines at least 2 hours apart from each dose where possible.
- Do not exceed 4 doses in 24 hours.
Duration of use and the 500ml pack
- Do not use continuously for more than 7 days without pharmacist or GP advice, regardless of pack size.
- Despite the larger 500ml volume, the bottle must be discarded 28 days after first opening. Do not continue using product beyond this point even if it appears unchanged, as the preservative effectiveness cannot be guaranteed after 28 days of opening.
Lifestyle considerations
- Avoid large meals, particularly in the evening, and eating within 2 to 3 hours of going to bed.
- Reduce alcohol, caffeine, fatty and spicy foods, and carbonated drinks where possible.
- Elevating the head of your bed can help reduce nocturnal reflux symptoms.
When to seek medical advice
- Symptoms do not improve after 7 days of treatment.
- You experience difficulty or pain swallowing.
- You have unexplained weight loss, persistent vomiting, or blood in vomit or stools.
- Symptoms are severe or significantly affecting quality of life.
Our Pearl Chemist Group pharmacists offer free consultations and can advise whether a GP referral is appropriate.
Full Ingredients in Acidex Advance Oral Suspension Aniseed Flavour 500ml
Active ingredients per 5ml dose: sodium alginate 200mg, sodium bicarbonate 133.5mg, calcium carbonate 80mg.
Excipients (inactive ingredients)
- Carbomer — thickening and suspending agent that maintains consistent viscosity and even distribution of active ingredients throughout the suspension
- Methyl parahydroxybenzoate (E218) — preservative that prevents microbial growth after opening
- Propyl parahydroxybenzoate (E216) — second preservative providing broad-spectrum antimicrobial protection; those with known paraben sensitivity should note its presence
- Sodium saccharin — artificial sweetener providing palatability without adding sugar
- Aniseed flavour — provides the characteristic aniseed taste of this variant
- Purified water — aqueous base of the suspension
If you have a known allergy to parabens (E216 or E218) or any other listed ingredient, do not use this product. Speak to a Pearl Chemist Group pharmacist for an alternative formulation.
Last reviewed: May 2026.
Always read the patient information leaflet before use. A copy is included in the pack. For advice, speak to a Pearl Chemist pharmacist or call +44 (0)20 8672 2157.
What Is Acidex Advance Oral Suspension Aniseed Flavour Used For?
Heartburn, acid reflux, and indigestion are everyday realities for a significant proportion of people across the UK. The familiar burning sensation rising from the stomach into the chest and throat, the sour taste of acid coming back up, and the discomfort of indigestion after meals can all disrupt eating, sleep, and general wellbeing. Acidex Advance Oral Suspension Aniseed Flavour is an alginate-based antacid suspension designed to help relieve these symptoms by creating a physical protective raft in the stomach that helps prevent acid from refluxing into the oesophagus. The 500ml bottle is an economy-sized format of the same proven formulation, offering excellent value for those who use the product regularly or wish to keep a supply at home without frequent repurchasing.
Acidex Advance works through a dual-action approach that sets it apart from simple antacid preparations. When the suspension reaches the stomach, sodium alginate reacts with natural stomach acid to form a thick, cohesive gel. Sodium bicarbonate simultaneously generates carbon dioxide, which makes this gel buoyant, causing it to rise and float on the surface of the stomach contents as a physical raft. This raft acts as a mechanical barrier, helping to physically prevent stomach acid and contents from refluxing upward into the oesophagus. Calcium carbonate provides additional antacid activity by directly neutralising excess stomach acid and helping to reinforce the structural integrity of the raft. Together, these three active ingredients address both the mechanical trigger of reflux and the chemical irritation it causes.
The 500ml suspension format is particularly practical for those who experience reflux regularly and prefer to dose after each meal and at bedtime as directed, as well as for households where more than one person uses the product. The aniseed flavour makes it a pleasant and palatable preparation to take, and the liquid format is especially useful for those who find tablets or capsules difficult to swallow. The bottle should always be shaken well before each dose and stored below 25°C. Please note that, as with all opened oral liquid preparations, the bottle should be discarded 28 days after first opening, regardless of how much product remains.
Acidex Advance is suitable for adults and young people aged 12 and over. It is not recommended for children under 6 and caution is advised in children aged 6 to 11. Those on sodium-restricted diets, with kidney impairment, or taking other medicines should seek pharmacist advice before use. If your symptoms are severe, worsening, or persistent beyond one week, or are accompanied by difficulty swallowing, unexplained weight loss, or vomiting, seek prompt assessment from your GP. Speak to a Pearl Chemist Group pharmacist for guidance on whether this product is right for you, or browse our full heartburn and indigestion range for further options.
How to Use Acidex Advance Oral Suspension Aniseed Flavour 500ml
- Shake the bottle well before every dose. The active ingredients can settle in the bottle between uses. Shake thoroughly each time before measuring to ensure an accurate, consistent dose.
- Measure your dose accurately. Use a 5ml medicine measuring spoon or an oral dosing syringe. Do not estimate using a household teaspoon, which may not hold exactly 5ml and could result in under or over-dosing.
- Take after meals and at bedtime. For the raft to form effectively, there should be stomach contents for it to float on. Always take after eating rather than before meals or on an empty stomach.
- Swallow directly. Take the measured dose by mouth without mixing with water or other drinks, as dilution may reduce the effectiveness of the raft-forming mechanism.
- Remain upright after post-meal doses where possible. Staying upright for at least 20 to 30 minutes after a dose helps the raft to position itself optimally. The bedtime dose can be taken before lying down.
- Replace the cap and store correctly. Replace the cap firmly after every use. Write the date of opening on the label and keep the bottle stored below 25°C.
Practical tips for the 500ml pack
- Write the opening date on the bottle label immediately. Despite the larger size, the bottle must be discarded 28 days after opening to maintain safety and efficacy.
- If multiple members of a household are using the product, consider noting each person's opening date separately if a second bottle is opened at a different time.
- Take any other medicines at least 2 hours before or after a dose of Acidex Advance to minimise the risk of interaction.
Acidex Advance Oral Suspension Aniseed Flavour 500ml Side Effects
Acidex Advance Oral Suspension is generally well tolerated when used as directed. Side effects are uncommon.
Common side effects (may affect more than 1 in 10 people)
- Increased wind or bloating as a result of the carbon dioxide generated during raft formation — this is a normal consequence of how the product works and is usually mild and temporary
Less common side effects (may affect between 1 in 10 and 1 in 100 people)
- Nausea or an unpleasant taste, particularly if taken in large quantities
- Constipation, associated with the calcium carbonate component
- Diarrhoea in some individuals
- Mild stomach discomfort or cramping
Rare side effects (may affect fewer than 1 in 100 people)
- Allergic reaction to one or more ingredients, including parabens, presenting as skin rash, itching, or swelling
- Electrolyte imbalance with excessive or prolonged use in those with kidney impairment
Stop using and seek medical help if you experience:
- A serious allergic reaction including significant facial or throat swelling, difficulty breathing, or a widespread rash — call 999 immediately
- Severe or worsening abdominal pain
- Any symptom that concerns you or that you believe may be related to this product
Report any unexpected reaction via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk or speak to your Pearl Chemist Group pharmacist.
How to Store Acidex Advance Oral Suspension Aniseed Flavour 500ml
- Temperature: Store below 25°C. Keep away from direct sunlight and sources of heat.
- Do not refrigerate.
- After opening: Discard 28 days after first opening regardless of how much product remains in the 500ml bottle. Write the date of opening on the label immediately.
- Before each use: Shake well before measuring each dose.
- Cap: Replace the cap firmly after every use.
- Children: Keep out of the sight and reach of children at all times.
- Expiry: Do not use after the expiry date printed on the bottle and outer packaging.
- Disposal: Do not dispose of via wastewater or household waste. Ask your Pearl Chemist Group pharmacist about safe disposal.
Who Is Acidex Advance Oral Suspension Aniseed Flavour 500ml Suitable For?
Acidex Advance Oral Suspension Aniseed Flavour 500ml is suitable for adults and young people aged 12 and over who experience symptoms of gastro-oesophageal reflux, including heartburn, acid regurgitation, and indigestion, and who prefer or require an economy-sized liquid format for regular or household use.
Suitable for:
- Adults aged 18 and over experiencing heartburn, acid reflux, or indigestion after meals or at night
- Young people aged 12 to 17, subject to appropriate adult supervision
- Those who use the product regularly and prefer an economy pack size to reduce the frequency of repurchasing
- Households where more than one person uses the product
- Those who prefer a liquid suspension over tablets or capsules, including people who find swallowing tablets difficult
- People who find alginate-based raft-forming preparations more effective for their reflux than simple antacids
- Those who experience nocturnal reflux or symptoms that disturb sleep
Not suitable for:
- Children under 6 years of age
- Children aged 6 to 11 years, unless specifically directed by a doctor
- Anyone with a known allergy or hypersensitivity to sodium alginate, sodium bicarbonate, calcium carbonate, parabens (E216/E218), or any other ingredient
Use with caution or seek advice first if you:
- Are on a sodium-restricted diet, as each dose contains a significant amount of sodium
- Have impaired kidney function
- Are taking any other prescribed or over-the-counter medicines
- Are pregnant or breastfeeding
- Have symptoms that are severe, persistent beyond 7 days, or accompanied by difficulty swallowing, weight loss, or vomiting
Our Pearl Chemist Group pharmacists are always available to help you confirm whether this product is appropriate for your symptoms and circumstances.
Active Ingredients in Acidex Advance Oral Suspension Aniseed Flavour 500ml
| Ingredient | Strength per 5ml dose | Role |
|---|---|---|
| Sodium alginate | 200mg | The primary active and raft-forming ingredient. Derived from brown seaweed, sodium alginate reacts with stomach acid to form a thick, cohesive gel that floats on the stomach contents as a physical raft, helping to mechanically prevent acid from refluxing up into the oesophagus. |
| Sodium bicarbonate | 133.5mg | Reacts with stomach acid to release carbon dioxide, making the alginate gel buoyant so that it floats effectively on the stomach contents. Also provides mild direct antacid activity by neutralising excess stomach acid. |
| Calcium carbonate | 80mg | Provides additional antacid activity by neutralising excess stomach acid directly. Also helps to reinforce and stabilise the physical structure of the alginate raft. |
Acidex Advance Oral Suspension Aniseed Flavour 500ml Dosage — How Much to Take
Adults and young people aged 12 and over
- Dose: 10–20ml (2 to 4 x 5ml spoonfuls) per dose.
- When to take: After meals and at bedtime.
- Maximum daily dose: 4 doses in any 24-hour period (maximum 80ml per day).
- How to take: Shake the bottle well before each use. Measure using a 5ml medicine spoon or oral syringe. Take orally after food.
Children aged 6 to 11 years
5–10ml after meals and at bedtime, under direct medical supervision only.
Children under 6 years
Not recommended.
Elderly patients
No specific dose adjustment required. Use the standard adult dose with caution if kidney function is impaired — seek pharmacist or GP guidance first.
Important dosage notes
- Do not exceed 4 doses in 24 hours.
- Always shake the bottle thoroughly before each dose.
- Do not use continuously for more than 7 days without consulting a pharmacist or GP.
- Discard the bottle 28 days after opening, even for a 500ml pack where product remains.
Precautions When Using Acidex Advance Oral Suspension Aniseed Flavour 500ml
Before you use this product
- Check the expiry date on the bottle and outer packaging.
- Check that the bottle seal is intact before first opening.
- Review drug interactions and consult your pharmacist if you take any regular medicines.
- If on a sodium-restricted diet or with kidney disease, seek pharmacist or GP advice before use.
During use
- Shake well before every dose.
- Measure accurately using a 5ml spoon or oral syringe.
- Do not mix with other drinks before taking.
- Take other medicines at least 2 hours apart from each dose where possible.
- Do not exceed 4 doses in 24 hours.
Duration of use and the 500ml pack
- Do not use continuously for more than 7 days without pharmacist or GP advice, regardless of pack size.
- Despite the larger 500ml volume, the bottle must be discarded 28 days after first opening. Do not continue using product beyond this point even if it appears unchanged, as the preservative effectiveness cannot be guaranteed after 28 days of opening.
Lifestyle considerations
- Avoid large meals, particularly in the evening, and eating within 2 to 3 hours of going to bed.
- Reduce alcohol, caffeine, fatty and spicy foods, and carbonated drinks where possible.
- Elevating the head of your bed can help reduce nocturnal reflux symptoms.
When to seek medical advice
- Symptoms do not improve after 7 days of treatment.
- You experience difficulty or pain swallowing.
- You have unexplained weight loss, persistent vomiting, or blood in vomit or stools.
- Symptoms are severe or significantly affecting quality of life.
Our Pearl Chemist Group pharmacists offer free consultations and can advise whether a GP referral is appropriate.
Full Ingredients in Acidex Advance Oral Suspension Aniseed Flavour 500ml
Active ingredients per 5ml dose: sodium alginate 200mg, sodium bicarbonate 133.5mg, calcium carbonate 80mg.
Excipients (inactive ingredients)
- Carbomer — thickening and suspending agent that maintains consistent viscosity and even distribution of active ingredients throughout the suspension
- Methyl parahydroxybenzoate (E218) — preservative that prevents microbial growth after opening
- Propyl parahydroxybenzoate (E216) — second preservative providing broad-spectrum antimicrobial protection; those with known paraben sensitivity should note its presence
- Sodium saccharin — artificial sweetener providing palatability without adding sugar
- Aniseed flavour — provides the characteristic aniseed taste of this variant
- Purified water — aqueous base of the suspension
If you have a known allergy to parabens (E216 or E218) or any other listed ingredient, do not use this product. Speak to a Pearl Chemist Group pharmacist for an alternative formulation.
Last reviewed: May 2026.
Always read the patient information leaflet before use. A copy is included in the pack. For advice, speak to a Pearl Chemist pharmacist or call +44 (0)20 8672 2157.
FAQs
Yes. Acidex Advance Oral Suspension Aniseed Flavour 500ml contains exactly the same formulation as the 250ml variant — the same active ingredients at identical strengths per 5ml dose, and the same excipients. The 500ml format is simply an economy-sized pack designed to offer better value for those who use the product regularly or prefer to keep a larger supply at home.
Yes. Regardless of pack size, Acidex Advance Oral Suspension must be discarded 28 days after first opening. This is because the preservative system in the suspension is designed to protect the product for 28 days after the seal is broken. Beyond this point, microbial contamination becomes a risk even if the suspension appears unchanged. Write the opening date on the label immediately to keep track. If the full 500ml is unlikely to be used within 28 days, you may wish to consider purchasing the 250ml size instead.
Standard antacid tablets work primarily by neutralising stomach acid chemically. Acidex Advance does this too, through its sodium bicarbonate and calcium carbonate components, but its key distinguishing feature is the sodium alginate, which forms a physical raft on the surface of the stomach contents. This raft physically blocks acid from flowing back into the oesophagus, addressing the mechanical cause of reflux rather than just the acidity. This dual action can make it more effective than simple antacids alone for those whose main symptom is reflux or regurgitation.
For best results, take Acidex Advance after meals and at bedtime. Taking it after food ensures there are stomach contents for the alginate raft to form on and float above. The bedtime dose is particularly valuable for those who experience acid reflux at night or in the early hours. Avoid taking the suspension on an empty stomach, where the raft-forming mechanism is less effective.
Antacid preparations can affect the absorption of a number of other medicines, including certain antibiotics, iron supplements, thyroid hormones, and bisphosphonates. As a general rule, take any other medicines at least 2 hours before or after a dose of Acidex Advance. If you take regular prescribed medicines, speak to a Pearl Chemist Group pharmacist before starting this product to identify any specific interactions relevant to your situation.
Each dose of Acidex Advance contains a notable amount of sodium from both the sodium alginate and sodium bicarbonate components. If you have been advised by your doctor to follow a low-sodium diet, for example due to heart failure, high blood pressure, or kidney disease, you should consult your GP or pharmacist before using this product regularly. They can advise on appropriate alternatives or help you manage the sodium contribution within your overall dietary limits.
If you need to use Acidex Advance continuously for more than 7 days, we recommend speaking to your GP or pharmacist. Frequent or persistent reflux symptoms can sometimes indicate an underlying condition such as gastro-oesophageal reflux disease (GORD), a hiatus hernia, or in rare cases something requiring further investigation. If your symptoms are accompanied by difficulty swallowing, unexplained weight loss, persistent vomiting, or blood in your vomit or stools, seek medical advice promptly rather than continuing to self-treat.
Heartburn is very common in pregnancy, particularly in the second and third trimesters, and alginate-based antacid suspensions are frequently discussed as a management option. However, the sodium content of each dose is an important consideration during pregnancy, particularly for women who have been advised to monitor their sodium intake. We recommend consulting your GP or midwife before using Acidex Advance during pregnancy to confirm that it is appropriate for your individual circumstances.