Acidex Advance Oral Suspension Peppermint Flavour 200mg/1000mg – 250ml

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What Is Acidex Advance Oral Suspension Peppermint Flavour Used For?
Heartburn, acid regurgitation, and indigestion caused by gastro-oesophageal reflux are among the most frequently reported digestive complaints in the UK, affecting people of all ages and often recurring after meals, in the evening, or during the night. Acidex Advance Oral Suspension Peppermint Flavour is an alginate-based antacid suspension formulated to help relieve these symptoms, offering the same proven dual-action formula as the aniseed variant in a peppermint flavour that many people find cool, fresh, and particularly soothing for symptoms of heartburn. The 250ml bottle provides a practical and convenient pack size for at-home use, making it easy to keep to the recommended after-meal and bedtime dosing routine.
The mechanism of action of Acidex Advance combines physical raft formation with direct antacid activity. When taken after a meal, sodium alginate reacts with the natural acid in the stomach to form a thick, buoyant gel raft on the surface of the stomach contents. This raft acts as a physical barrier, helping to prevent acid and stomach contents from refluxing upward into the oesophagus where they cause the burning discomfort of heartburn. Sodium bicarbonate generates the carbon dioxide needed to keep the raft buoyant and also provides mild direct acid-neutralising activity. Calcium carbonate contributes further antacid action and helps to stabilise the raft's structure. The combined effect addresses both the mechanical cause of reflux and the excess acidity that makes the symptoms so uncomfortable.
The peppermint flavour option is a popular choice for those who prefer a cool, refreshing taste over the aniseed variant, and the fresh minty aftertaste may feel particularly pleasant when heartburn symptoms are present. As with all variants of Acidex Advance, the suspension should be shaken thoroughly before each dose, measured accurately using a 5ml spoon or oral dosing syringe, and taken after food for best effect. The bottle should be discarded 28 days after opening.
Acidex Advance is suitable for adults and young people aged 12 and over. Those on sodium-restricted diets, with kidney problems, or taking other regular medicines should seek pharmacist advice before use. If you experience symptoms that are severe, persistent beyond one week, or accompanied by difficulty swallowing, unexplained weight loss, or vomiting, consult your GP promptly. Our Pearl Chemist Group pharmacists are happy to advise, and you can also view our full heartburn and indigestion range for further options.
How to Use Acidex Advance Oral Suspension Peppermint Flavour 250ml
- Shake the bottle well before every dose. Active ingredients may settle between uses. Shake thoroughly before measuring to ensure a consistent, accurate dose every time.
- Measure your dose accurately. Use a calibrated 5ml medicine spoon or oral dosing syringe. Avoid household teaspoons, which may not deliver exactly 5ml.
- Take after meals and at bedtime. Taking after food ensures there are stomach contents for the alginate raft to form on and float above, maximising the product's effectiveness.
- Swallow directly without mixing. Take the dose by mouth without diluting with water or other drinks, as this may reduce the raft-forming effectiveness.
- Remain upright after post-meal doses where possible. Staying upright for 20 to 30 minutes after a dose helps the raft to work optimally. The bedtime dose may be taken before lying down.
- Replace the cap securely after every use. Write the date of opening on the label and store below 25°C.
Practical tips
- Take any other medicines at least 2 hours before or after each dose to minimise the risk of interaction with the antacid components.
- If a dose is missed, take it as soon as you remember. If it is nearly time for the next dose, skip the missed dose and continue as normal. Do not double up.
- Discard the bottle 28 days after opening.
Acidex Advance Oral Suspension Peppermint Flavour 250ml Side Effects
Acidex Advance Oral Suspension is generally well tolerated when used as directed.
Common side effects (may affect more than 1 in 10 people)
- Increased wind or bloating due to carbon dioxide released during raft formation — normal and usually mild and temporary
Less common side effects (may affect between 1 in 10 and 1 in 100 people)
- Nausea or unpleasant taste, particularly with larger doses
- Constipation, related to the calcium carbonate component
- Diarrhoea in some individuals
- Mild stomach discomfort or cramping
Rare side effects (may affect fewer than 1 in 100 people)
- Allergic reaction to one or more ingredients including parabens, presenting as rash, itching, or swelling
- Sensitivity reaction to peppermint flavouring in susceptible individuals
Stop using and seek medical help if you experience:
- A serious allergic reaction including significant facial or throat swelling, difficulty breathing, or a widespread rash — call 999 immediately
- Severe or worsening abdominal pain
- Any symptom that concerns you or that you believe may be related to this product
Report any unexpected reaction via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk or speak to your Pearl Chemist Group pharmacist.
How to Store Acidex Advance Oral Suspension Peppermint Flavour 250ml
- Temperature: Store below 25°C. Keep away from direct sunlight and heat sources.
- Do not refrigerate.
- After opening: Discard 28 days after first opening. Write the opening date on the label.
- Before each use: Shake well before measuring each dose.
- Cap: Replace firmly after every use.
- Children: Keep out of the sight and reach of children.
- Expiry: Do not use after the expiry date printed on the bottle and outer packaging.
- Disposal: Ask your Pearl Chemist Group pharmacist about safe disposal of medicines you no longer need.
Who Is Acidex Advance Oral Suspension Peppermint Flavour 250ml Suitable For?
Acidex Advance Oral Suspension Peppermint Flavour 250ml is suitable for adults and young people aged 12 and over who experience symptoms of gastro-oesophageal reflux, including heartburn, acid regurgitation, and indigestion, and who prefer a peppermint-flavoured liquid suspension.
Suitable for:
- Adults aged 18 and over experiencing heartburn, acid reflux, or indigestion after meals or at night
- Young people aged 12 to 17, subject to appropriate adult supervision
- Those who prefer a peppermint flavour over aniseed in their antacid preparation
- Those who prefer a liquid suspension over tablets or capsules
- People who find alginate-based raft-forming preparations more effective for their reflux symptoms than simple antacids
- Those who experience nocturnal reflux or symptoms that disturb sleep
- Pregnant women experiencing heartburn, subject to GP or midwife guidance on sodium content
Not suitable for:
- Children under 6 years of age
- Children aged 6 to 11 years unless specifically directed by a doctor
- Anyone with a known allergy or hypersensitivity to any ingredient including parabens (E216/E218)
- Those with a known sensitivity to peppermint or menthol-containing preparations
Use with caution or seek advice first if you:
- Are on a sodium-restricted diet
- Have impaired kidney function
- Are taking any prescribed or over-the-counter medicines
- Are pregnant or breastfeeding
- Have severe, persistent, or worsening symptoms, or symptoms accompanied by difficulty swallowing, weight loss, or vomiting
Speak to a Pearl Chemist Group pharmacist for free, personalised guidance.
Active Ingredients in Acidex Advance Oral Suspension Peppermint Flavour 250ml
| Ingredient | Strength per 5ml dose | Role |
|---|---|---|
| Sodium alginate | 200mg | The primary raft-forming active ingredient. Derived from brown seaweed, sodium alginate reacts with stomach acid to form a thick, cohesive, buoyant gel raft on the surface of the stomach contents, creating a physical barrier that helps prevent acid from refluxing into the oesophagus. |
| Sodium bicarbonate | 133.5mg | Generates carbon dioxide on contact with stomach acid, making the alginate raft buoyant so it floats effectively on stomach contents. Provides mild additional antacid activity by directly neutralising excess stomach acid. |
| Calcium carbonate | 80mg | Provides antacid activity by neutralising excess stomach acid directly. Also helps to reinforce and stabilise the structural integrity of the alginate raft. |
Acidex Advance Oral Suspension Peppermint Flavour 250ml Dosage — How Much to Take
Adults and young people aged 12 and over
- Dose: 10–20ml (2 to 4 x 5ml spoonfuls) per dose.
- When to take: After meals and at bedtime.
- Maximum daily dose: 4 doses in any 24-hour period (maximum 80ml per day).
- How to take: Shake well before use. Measure with a 5ml medicine spoon or oral syringe. Take orally after food.
Children aged 6 to 11 years
5–10ml after meals and at bedtime, under medical supervision only.
Children under 6 years
Not recommended.
Elderly patients
Standard adult dosage applies. Use with caution if kidney function is impaired — consult pharmacist or GP first.
Important dosage notes
- Do not exceed 4 doses in 24 hours.
- Always shake the bottle well before each dose.
- Do not use continuously for more than 7 days without seeking pharmacist or GP guidance.
- Discard 28 days after opening.
Precautions When Using Acidex Advance Oral Suspension Peppermint Flavour 250ml
Before you use this product
- Check the expiry date on the bottle and outer packaging.
- Check the bottle seal is intact before first opening.
- Review drug interactions and consult your pharmacist if you take any regular medicines.
- If on a sodium-restricted diet or with kidney disease, seek advice before use.
- If you have a known sensitivity to peppermint or menthol, do not use this variant — consider the aniseed flavour instead.
During use
- Shake well before every dose.
- Measure accurately with a 5ml spoon or oral syringe.
- Do not mix with other drinks before taking.
- Allow at least 2 hours between Acidex Advance and any other medicines.
- Do not exceed 4 doses in 24 hours.
Duration of use
- Do not use continuously for more than 7 days without pharmacist or GP guidance.
- Discard 28 days after opening.
Lifestyle considerations
- Avoid large meals in the evening and eating within 2 to 3 hours of bedtime.
- Reduce alcohol, caffeine, fatty and spicy foods, and carbonated drinks where possible.
- Consider elevating the head of your bed to reduce nocturnal symptoms.
When to seek medical advice
- Symptoms do not improve after 7 days.
- You experience difficulty or pain swallowing.
- You have unexplained weight loss, persistent vomiting, or blood in vomit or stools.
- Symptoms are severe or significantly affecting quality of life.
Our Pearl Chemist Group pharmacists offer free consultations and can advise on whether a GP referral is appropriate.
Full Ingredients in Acidex Advance Oral Suspension Peppermint Flavour 250ml
Active ingredients per 5ml dose: sodium alginate 200mg, sodium bicarbonate 133.5mg, calcium carbonate 80mg.
Excipients (inactive ingredients)
- Carbomer — thickening and suspending agent maintaining consistent viscosity and even distribution of active ingredients
- Methyl parahydroxybenzoate (E218) — preservative preventing microbial growth after opening
- Propyl parahydroxybenzoate (E216) — second preservative providing broad-spectrum antimicrobial protection; those with known paraben sensitivity should note its presence
- Sodium saccharin — artificial sweetener providing palatability without adding sugar
- Peppermint flavour — provides the characteristic cool, fresh peppermint taste of this variant
- Purified water — aqueous base of the suspension
If you have a known allergy to parabens (E216 or E218), peppermint, or any other listed ingredient, do not use this product. Speak to a Pearl Chemist Group pharmacist for an alternative formulation such as the aniseed variant.
Last reviewed: May 2026.
Always read the patient information leaflet before use. A copy is included in the pack. For advice, speak to a Pearl Chemist pharmacist or call +44 (0)20 8672 2157.
What Is Acidex Advance Oral Suspension Peppermint Flavour Used For?
Heartburn, acid regurgitation, and indigestion caused by gastro-oesophageal reflux are among the most frequently reported digestive complaints in the UK, affecting people of all ages and often recurring after meals, in the evening, or during the night. Acidex Advance Oral Suspension Peppermint Flavour is an alginate-based antacid suspension formulated to help relieve these symptoms, offering the same proven dual-action formula as the aniseed variant in a peppermint flavour that many people find cool, fresh, and particularly soothing for symptoms of heartburn. The 250ml bottle provides a practical and convenient pack size for at-home use, making it easy to keep to the recommended after-meal and bedtime dosing routine.
The mechanism of action of Acidex Advance combines physical raft formation with direct antacid activity. When taken after a meal, sodium alginate reacts with the natural acid in the stomach to form a thick, buoyant gel raft on the surface of the stomach contents. This raft acts as a physical barrier, helping to prevent acid and stomach contents from refluxing upward into the oesophagus where they cause the burning discomfort of heartburn. Sodium bicarbonate generates the carbon dioxide needed to keep the raft buoyant and also provides mild direct acid-neutralising activity. Calcium carbonate contributes further antacid action and helps to stabilise the raft's structure. The combined effect addresses both the mechanical cause of reflux and the excess acidity that makes the symptoms so uncomfortable.
The peppermint flavour option is a popular choice for those who prefer a cool, refreshing taste over the aniseed variant, and the fresh minty aftertaste may feel particularly pleasant when heartburn symptoms are present. As with all variants of Acidex Advance, the suspension should be shaken thoroughly before each dose, measured accurately using a 5ml spoon or oral dosing syringe, and taken after food for best effect. The bottle should be discarded 28 days after opening.
Acidex Advance is suitable for adults and young people aged 12 and over. Those on sodium-restricted diets, with kidney problems, or taking other regular medicines should seek pharmacist advice before use. If you experience symptoms that are severe, persistent beyond one week, or accompanied by difficulty swallowing, unexplained weight loss, or vomiting, consult your GP promptly. Our Pearl Chemist Group pharmacists are happy to advise, and you can also view our full heartburn and indigestion range for further options.
How to Use Acidex Advance Oral Suspension Peppermint Flavour 250ml
- Shake the bottle well before every dose. Active ingredients may settle between uses. Shake thoroughly before measuring to ensure a consistent, accurate dose every time.
- Measure your dose accurately. Use a calibrated 5ml medicine spoon or oral dosing syringe. Avoid household teaspoons, which may not deliver exactly 5ml.
- Take after meals and at bedtime. Taking after food ensures there are stomach contents for the alginate raft to form on and float above, maximising the product's effectiveness.
- Swallow directly without mixing. Take the dose by mouth without diluting with water or other drinks, as this may reduce the raft-forming effectiveness.
- Remain upright after post-meal doses where possible. Staying upright for 20 to 30 minutes after a dose helps the raft to work optimally. The bedtime dose may be taken before lying down.
- Replace the cap securely after every use. Write the date of opening on the label and store below 25°C.
Practical tips
- Take any other medicines at least 2 hours before or after each dose to minimise the risk of interaction with the antacid components.
- If a dose is missed, take it as soon as you remember. If it is nearly time for the next dose, skip the missed dose and continue as normal. Do not double up.
- Discard the bottle 28 days after opening.
Acidex Advance Oral Suspension Peppermint Flavour 250ml Side Effects
Acidex Advance Oral Suspension is generally well tolerated when used as directed.
Common side effects (may affect more than 1 in 10 people)
- Increased wind or bloating due to carbon dioxide released during raft formation — normal and usually mild and temporary
Less common side effects (may affect between 1 in 10 and 1 in 100 people)
- Nausea or unpleasant taste, particularly with larger doses
- Constipation, related to the calcium carbonate component
- Diarrhoea in some individuals
- Mild stomach discomfort or cramping
Rare side effects (may affect fewer than 1 in 100 people)
- Allergic reaction to one or more ingredients including parabens, presenting as rash, itching, or swelling
- Sensitivity reaction to peppermint flavouring in susceptible individuals
Stop using and seek medical help if you experience:
- A serious allergic reaction including significant facial or throat swelling, difficulty breathing, or a widespread rash — call 999 immediately
- Severe or worsening abdominal pain
- Any symptom that concerns you or that you believe may be related to this product
Report any unexpected reaction via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk or speak to your Pearl Chemist Group pharmacist.
How to Store Acidex Advance Oral Suspension Peppermint Flavour 250ml
- Temperature: Store below 25°C. Keep away from direct sunlight and heat sources.
- Do not refrigerate.
- After opening: Discard 28 days after first opening. Write the opening date on the label.
- Before each use: Shake well before measuring each dose.
- Cap: Replace firmly after every use.
- Children: Keep out of the sight and reach of children.
- Expiry: Do not use after the expiry date printed on the bottle and outer packaging.
- Disposal: Ask your Pearl Chemist Group pharmacist about safe disposal of medicines you no longer need.
Who Is Acidex Advance Oral Suspension Peppermint Flavour 250ml Suitable For?
Acidex Advance Oral Suspension Peppermint Flavour 250ml is suitable for adults and young people aged 12 and over who experience symptoms of gastro-oesophageal reflux, including heartburn, acid regurgitation, and indigestion, and who prefer a peppermint-flavoured liquid suspension.
Suitable for:
- Adults aged 18 and over experiencing heartburn, acid reflux, or indigestion after meals or at night
- Young people aged 12 to 17, subject to appropriate adult supervision
- Those who prefer a peppermint flavour over aniseed in their antacid preparation
- Those who prefer a liquid suspension over tablets or capsules
- People who find alginate-based raft-forming preparations more effective for their reflux symptoms than simple antacids
- Those who experience nocturnal reflux or symptoms that disturb sleep
- Pregnant women experiencing heartburn, subject to GP or midwife guidance on sodium content
Not suitable for:
- Children under 6 years of age
- Children aged 6 to 11 years unless specifically directed by a doctor
- Anyone with a known allergy or hypersensitivity to any ingredient including parabens (E216/E218)
- Those with a known sensitivity to peppermint or menthol-containing preparations
Use with caution or seek advice first if you:
- Are on a sodium-restricted diet
- Have impaired kidney function
- Are taking any prescribed or over-the-counter medicines
- Are pregnant or breastfeeding
- Have severe, persistent, or worsening symptoms, or symptoms accompanied by difficulty swallowing, weight loss, or vomiting
Speak to a Pearl Chemist Group pharmacist for free, personalised guidance.
Active Ingredients in Acidex Advance Oral Suspension Peppermint Flavour 250ml
| Ingredient | Strength per 5ml dose | Role |
|---|---|---|
| Sodium alginate | 200mg | The primary raft-forming active ingredient. Derived from brown seaweed, sodium alginate reacts with stomach acid to form a thick, cohesive, buoyant gel raft on the surface of the stomach contents, creating a physical barrier that helps prevent acid from refluxing into the oesophagus. |
| Sodium bicarbonate | 133.5mg | Generates carbon dioxide on contact with stomach acid, making the alginate raft buoyant so it floats effectively on stomach contents. Provides mild additional antacid activity by directly neutralising excess stomach acid. |
| Calcium carbonate | 80mg | Provides antacid activity by neutralising excess stomach acid directly. Also helps to reinforce and stabilise the structural integrity of the alginate raft. |
Acidex Advance Oral Suspension Peppermint Flavour 250ml Dosage — How Much to Take
Adults and young people aged 12 and over
- Dose: 10–20ml (2 to 4 x 5ml spoonfuls) per dose.
- When to take: After meals and at bedtime.
- Maximum daily dose: 4 doses in any 24-hour period (maximum 80ml per day).
- How to take: Shake well before use. Measure with a 5ml medicine spoon or oral syringe. Take orally after food.
Children aged 6 to 11 years
5–10ml after meals and at bedtime, under medical supervision only.
Children under 6 years
Not recommended.
Elderly patients
Standard adult dosage applies. Use with caution if kidney function is impaired — consult pharmacist or GP first.
Important dosage notes
- Do not exceed 4 doses in 24 hours.
- Always shake the bottle well before each dose.
- Do not use continuously for more than 7 days without seeking pharmacist or GP guidance.
- Discard 28 days after opening.
Precautions When Using Acidex Advance Oral Suspension Peppermint Flavour 250ml
Before you use this product
- Check the expiry date on the bottle and outer packaging.
- Check the bottle seal is intact before first opening.
- Review drug interactions and consult your pharmacist if you take any regular medicines.
- If on a sodium-restricted diet or with kidney disease, seek advice before use.
- If you have a known sensitivity to peppermint or menthol, do not use this variant — consider the aniseed flavour instead.
During use
- Shake well before every dose.
- Measure accurately with a 5ml spoon or oral syringe.
- Do not mix with other drinks before taking.
- Allow at least 2 hours between Acidex Advance and any other medicines.
- Do not exceed 4 doses in 24 hours.
Duration of use
- Do not use continuously for more than 7 days without pharmacist or GP guidance.
- Discard 28 days after opening.
Lifestyle considerations
- Avoid large meals in the evening and eating within 2 to 3 hours of bedtime.
- Reduce alcohol, caffeine, fatty and spicy foods, and carbonated drinks where possible.
- Consider elevating the head of your bed to reduce nocturnal symptoms.
When to seek medical advice
- Symptoms do not improve after 7 days.
- You experience difficulty or pain swallowing.
- You have unexplained weight loss, persistent vomiting, or blood in vomit or stools.
- Symptoms are severe or significantly affecting quality of life.
Our Pearl Chemist Group pharmacists offer free consultations and can advise on whether a GP referral is appropriate.
Full Ingredients in Acidex Advance Oral Suspension Peppermint Flavour 250ml
Active ingredients per 5ml dose: sodium alginate 200mg, sodium bicarbonate 133.5mg, calcium carbonate 80mg.
Excipients (inactive ingredients)
- Carbomer — thickening and suspending agent maintaining consistent viscosity and even distribution of active ingredients
- Methyl parahydroxybenzoate (E218) — preservative preventing microbial growth after opening
- Propyl parahydroxybenzoate (E216) — second preservative providing broad-spectrum antimicrobial protection; those with known paraben sensitivity should note its presence
- Sodium saccharin — artificial sweetener providing palatability without adding sugar
- Peppermint flavour — provides the characteristic cool, fresh peppermint taste of this variant
- Purified water — aqueous base of the suspension
If you have a known allergy to parabens (E216 or E218), peppermint, or any other listed ingredient, do not use this product. Speak to a Pearl Chemist Group pharmacist for an alternative formulation such as the aniseed variant.
Last reviewed: May 2026.
Always read the patient information leaflet before use. A copy is included in the pack. For advice, speak to a Pearl Chemist pharmacist or call +44 (0)20 8672 2157.
FAQs
Yes, in terms of active ingredients and therapeutic action. Both the peppermint and aniseed variants of Acidex Advance contain identical active ingredients at the same strengths per 5ml dose — sodium alginate 200mg, sodium bicarbonate 133.5mg, and calcium carbonate 80mg — and work in exactly the same way. The only difference between the two is the flavouring used. The peppermint flavour provides a cool, fresh taste that many people find refreshing and particularly pleasant when experiencing heartburn symptoms.
If you have a known sensitivity or allergy to peppermint or menthol-containing preparations, you should avoid the peppermint flavour variant and use the aniseed flavour instead, which does not contain peppermint. If you are unsure whether you have a sensitivity, consult your Pearl Chemist Group pharmacist before starting either variant.
Simple antacid tablets primarily neutralise stomach acid chemically. Acidex Advance does this too through its sodium bicarbonate and calcium carbonate, but its key differentiating feature is sodium alginate, which forms a physical gel raft on the surface of the stomach contents. This raft physically blocks acid from refluxing back into the oesophagus, addressing the mechanical cause of reflux rather than just the acidity. This combined approach can be more effective for those whose main complaint is the sensation of acid rising rather than just excess acidity alone.
Take Acidex Advance after meals and at bedtime. Taking after food ensures there are stomach contents for the alginate raft to form on and float above. The bedtime dose is particularly helpful for those who experience reflux during the night or who wake with heartburn symptoms. Avoid taking on an empty stomach, as the raft-forming mechanism works best when there is food in the stomach.
In many cases, alginate antacid suspensions are used alongside prescribed medicines such as proton pump inhibitors (e.g. omeprazole) or H2 blockers for additional symptom control, particularly for breakthrough symptoms. However, antacids can affect the absorption of some medicines, so take other preparations at least 2 hours apart where possible. Confirm with your GP or pharmacist that this combination is appropriate for your specific medicines and circumstances before combining treatments.
Heartburn is very common in pregnancy, and alginate-based preparations are among the most frequently discussed options for managing it. However, the sodium content of each dose is an important consideration during pregnancy, particularly for women who have been advised to watch their sodium intake. Additionally, although peppermint flavouring in a suspension is generally considered safe, we recommend consulting your GP or midwife before using Acidex Advance during pregnancy to confirm that this specific product and flavour variant are appropriate for you.
Discard 28 days after first opening, even if product remains. Write the opening date on the label when you first use it. Beyond 28 days the preservative system cannot guarantee the suspension remains free from microbial contamination, even if it looks and smells unchanged.
If your symptoms have not improved after 7 days of regular use, you should consult your GP or pharmacist rather than continuing to self-treat. Persistent reflux symptoms can sometimes indicate an underlying condition such as gastro-oesophageal reflux disease (GORD) or a hiatus hernia, both of which may require specific medical management. If your symptoms are accompanied by difficulty swallowing, unexplained weight loss, or any bleeding, seek medical assessment promptly.