Alflorex Capsules – 30 Capsules

Alflorex contains a single, specifically characterised strain: Bifidobacterium longum 35624. This strain has been studied in multiple double-blind, placebo-controlled clinical trials specifically in patients with IBS — the gold standard of clinical evidence. The vast majority of consumer probiotic products are formulated on the basis of species-level evidence or general gut health associations, using strains that have never been individually evaluated in clinical trials. The 35624 strain's clinical research basis is genuinely exceptional and represents the standard that strain-specific probiotic science aspires to.

Bifidobacterium longum is a species of beneficial bacteria naturally resident in the human gut — particularly in the large intestine — and is one of the dominant bacterial species in infants. The 35624 designation identifies a specific individual strain within the B. longum species, isolated and characterised by researchers at University College Cork. Just as different varieties of the same plant species have different properties, different strains of B. longum have different characteristics, colonisation behaviour, and biological effects. The 35624 strain was selected through systematic screening for its specific properties relevant to digestive comfort and gut immune modulation.

The 35624 strain has been studied in multiple peer-reviewed clinical trials, including landmark studies published in Gastroenterology (O'Mahony et al., 2005) and the American Journal of Gastroenterology (Whorwell et al., 2006). In these trials, patients with IBS who took B. longum 35624 demonstrated statistically significant improvements in overall IBS symptom severity, abdominal bloating, cramping, and bowel habit normalisation compared with placebo. The Whorwell et al. study specifically found that the 35624 strain at one billion CFU significantly outperformed placebo for overall IBS symptom relief. This published evidence base is among the strongest for any commercially available probiotic.

Alflorex is a food supplement — it is not a medicine and does not claim to treat, cure, or prevent IBS. If you have been diagnosed with IBS, consult your GP or gastroenterologist for appropriate medical management. Alflorex may be considered as a complement to medical management — many gastroenterologists and GPs are familiar with the B. longum 35624 clinical literature and are supportive of patients incorporating Alflorex into their overall gut health approach. However, this should always be in dialogue with your healthcare team.

The choice to use a single, well-characterised strain rather than a multi-strain blend reflects the clinical research philosophy behind Alflorex. The 35624 strain has been specifically studied at a defined, validated dose. Adding multiple additional strains to the formula would make it impossible to attribute any observed benefit to the 35624 strain specifically, and would introduce strains whose interactions with 35624 have not been studied. The single-strain approach means each capsule delivers a consistent, precisely characterised dose of the exact strain supported by the clinical evidence.

In the clinical trials that studied B. longum 35624, meaningful improvements in IBS symptoms were observed within four weeks of consistent daily use. However, individual responses vary, and some participants in the trials noticed improvements earlier whilst others required the full study period. Consistent daily use over at least four to eight weeks — matching the trial durations — provides the most meaningful assessment of personal benefit. Do not judge the product's effect after a week or two.

Confirm the storage requirement from the current product label. Many probiotic capsules are now manufactured with enhanced stability that permits room-temperature storage before opening, with refrigeration recommended after opening to maintain viability over the duration of use. Always follow the specific storage guidance on the current label rather than assuming either room-temperature or refrigeration storage — the manufacturer's guidance is based on validated stability testing for this specific strain.

Alflorex can be taken alongside other probiotic products, but there is generally little evidence that combining multiple probiotic products provides additive benefit, and the interaction between different strains is not well studied in consumer supplementation contexts. If you are already taking another probiotic, consult your pharmacist about whether there is a clinical rationale for combining them or whether Alflorex alone is the most focused approach for your digestive health goals.