Allevia Fexofenadine Tablets 120mg – 15 Tablets

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What Are Allevia Fexofenadine 120mg Tablets Used For?
Hayfever is one of the most prevalent allergic conditions in the United Kingdom, affecting an estimated 13 million people and causing significant disruption to daily life, sleep, productivity, and wellbeing during the spring and summer pollen seasons. Sneezing, a relentlessly runny nose, itchy and streaming eyes, and an itchy throat and palate — often accompanied by fatigue from disrupted sleep — are all symptoms that many people endure for months each year. Allevia Fexofenadine Hydrochloride Tablets 120mg offer effective once-daily relief from these symptoms of seasonal allergic rhinitis without the drowsiness that limits the usefulness of many older antihistamine preparations. The 15-tablet pack is a convenient standard-sized supply for the hayfever season.
The active ingredient is fexofenadine hydrochloride at 120mg per tablet. Fexofenadine is a potent, highly selective, non-sedating antihistamine that works by competitively blocking histamine H1 receptors in the nasal mucosa, eyes, throat, and skin. When pollen or another seasonal allergen triggers an immune response in susceptible individuals, mast cells release histamine, which binds to H1 receptors and produces the characteristic symptoms of hayfever. Fexofenadine prevents this binding, blocking the histamine-driven cascade that causes sneezing, nasal secretion, itching, and eye irritation. A single 120mg dose provides sustained H1 receptor blockade for a full 24 hours, allowing once-daily dosing that fits easily into a morning routine and provides consistent, reliable coverage throughout the day and evening.
What sets fexofenadine apart from many other antihistamines available for hayfever is its particularly strong non-sedating profile. Unlike first-generation antihistamines and even some second-generation options, fexofenadine does not cross the blood-brain barrier to any clinically significant degree at therapeutic doses. This means it provides effective symptom relief without causing the drowsiness, impaired concentration, or reduced reaction time that can significantly affect driving safety and workplace performance. Clinical trials have shown its sedation rate to be statistically indistinguishable from placebo.
There is one important practical instruction that applies specifically to fexofenadine and has a meaningful impact on its effectiveness: it must always be taken with water, never with fruit juice. Grapefruit juice, orange juice, and apple juice all significantly reduce fexofenadine absorption and should be avoided around the time the tablet is taken. Allevia 120mg is suitable for adults and young people aged 12 and over, and is available as a General Sale medicine (GSL). Speak to a Pearl Chemist Group pharmacist for personalised hayfever management advice, or browse our full hayfever and allergy range.
How to Use Allevia Fexofenadine 120mg Tablets
- Take one tablet once daily. Remove one tablet from the blister and take it before a meal, at the same time each day.
- Always take with a full glass of plain water. Never take with fruit juice of any kind — grapefruit, orange, and apple juices all significantly reduce fexofenadine absorption. Plain water is the only suitable drink for taking this tablet.
- Swallow whole. Do not crush or chew the tablet.
- Take at the same time each day. Consistent daily dosing maintains effective, sustained antihistamine coverage and provides the best symptom control throughout the day and overnight.
- If you take antacids, time your doses carefully. Leave at least 2 hours between fexofenadine and any antacid containing aluminium or magnesium hydroxide.
Tips for best results during hayfever season
- Starting fexofenadine a few days before your hayfever season typically begins can help to establish effective coverage before symptoms peak.
- If you also suffer from eye symptoms, your pharmacist may recommend combining fexofenadine with an antihistamine eye drop for additional ocular relief.
- For those with significant nasal congestion that oral antihistamines alone do not fully address, a topical corticosteroid nasal spray used alongside daily fexofenadine often provides substantially better overall hayfever control.
Allevia Fexofenadine 120mg Tablets Side Effects
Fexofenadine is very well tolerated with a side effect profile closely comparable to placebo in clinical trials.
Common side effects (may affect more than 1 in 10 people)
- Headache
- Drowsiness — incidence is very low and comparable to placebo in clinical trials
Less common side effects (may affect between 1 in 10 and 1 in 100 people)
- Nausea or stomach upset
- Dizziness
- Fatigue
- Dry mouth
Rare side effects (may affect fewer than 1 in 100 people)
- Sleep disturbance
- Rapid or irregular heartbeat
- Skin rash or hypersensitivity reactions
Stop using and seek medical help if you experience:
- Rapid or irregular heartbeat that is new or persistent
- Signs of a serious allergic reaction — call 999 immediately
Report any unexpected reaction via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk or speak to your Pearl Chemist Group pharmacist.
How to Store Allevia Fexofenadine 120mg Tablets 15 Pack
- Temperature: Store below 30°C. Keep away from direct sunlight and heat sources.
- Packaging: Keep in the original blister pack inside the outer carton.
- Do not refrigerate.
- Children: Keep out of the sight and reach of children.
- Expiry: Do not use after the expiry date on the blister and outer packaging.
- Disposal: Return unused tablets to your Pearl Chemist Group pharmacy for safe disposal.
Who Are Allevia Fexofenadine 120mg Tablets Suitable For?
Allevia Fexofenadine Hydrochloride Tablets 120mg are suitable for adults and young people aged 12 and over who experience symptoms of seasonal allergic rhinitis (hayfever) and require effective, once-daily, non-sedating antihistamine relief.
Suitable for:
- Adults with sneezing, runny nose, nasal congestion, itchy and watery eyes, and itchy nose and throat caused by seasonal hayfever
- Young people aged 12 to 17, subject to appropriate adult supervision
- Those who need to drive, operate machinery, or maintain full alertness during hayfever treatment
- People who have found other antihistamines too sedating for daytime use
- Those who prefer a once-daily tablet for simplicity and consistent coverage
- People who experience hayfever symptoms across a substantial part of the pollen season and prefer a standard supply pack
Not suitable for:
- Children under 12 years of age
- Anyone with known hypersensitivity to fexofenadine hydrochloride, hydroxyzine, or any excipient
- Those with severe renal impairment without prior medical guidance
- Use for chronic idiopathic urticaria (hives) — the specifically licensed dose for urticaria is 180mg, not 120mg
Use with caution or seek advice first if you:
- Have any degree of renal impairment
- Are pregnant or breastfeeding
- Take antacids containing aluminium or magnesium hydroxide — separate doses by at least 2 hours
- Regularly consume large quantities of fruit juice with morning medicines
Our Pearl Chemist Group pharmacists are available for personalised hayfever management advice.
Active Ingredients in Allevia Fexofenadine 120mg Tablets
| Ingredient | Strength per tablet | Role |
|---|---|---|
| Fexofenadine hydrochloride | 120mg | A potent, highly selective, non-sedating antihistamine. Fexofenadine blocks peripheral histamine H1 receptors, preventing histamine — released in response to pollen and other seasonal allergens — from triggering the nasal, ocular, and throat symptoms of hayfever. A single 120mg dose provides 24-hour coverage, making once-daily dosing sufficient for consistent allergy control. Fexofenadine does not cross the blood-brain barrier to any clinically significant extent at this dose, which is the basis for its non-sedating, non-impairing profile that allows normal driving and workplace performance during treatment. |
Allevia Fexofenadine 120mg Tablets Dosage — How Much to Take
Adults and young people aged 12 and over
- Dose: 120mg (1 tablet) once daily.
- When to take: Before a meal, at the same time each day. Take with a full glass of water — never with fruit juice.
- Duration: Use throughout the hayfever season or as long as symptoms are present. Starting a few days before the expected onset of the pollen season may help to establish protective H1 receptor blockade before symptoms develop.
Children under 12 years
Not recommended.
Elderly patients
No dose adjustment is required in elderly patients with normal renal function. In those with impaired kidney function, consult your pharmacist or GP.
Critical instructions — fexofenadine absorption
- Always take with water — fruit juices significantly reduce absorption.
- Take before food for optimal absorption.
- Separate from antacid doses (aluminium or magnesium hydroxide-based) by at least 2 hours.
Precautions When Using Allevia Fexofenadine 120mg Tablets
Before use
- Check the expiry date on the blister and outer packaging.
- Confirm no hypersensitivity to fexofenadine or hydroxyzine.
- If you have renal impairment, seek pharmacist or GP guidance before use.
- Do not use during pregnancy or breastfeeding without medical guidance.
During use
- Always take with water, never with fruit juice.
- Take before food for best absorption.
- Separate doses from antacids by at least 2 hours.
- Take at the same time every day.
When to seek medical advice
- Hayfever symptoms are not adequately controlled despite consistent daily treatment.
- You develop new symptoms or your condition changes significantly.
- You experience any side effect that concerns you.
Our Pearl Chemist Group pharmacists can advise on comprehensive hayfever management strategies.
Full Ingredients in Allevia Fexofenadine 120mg Tablets
The active ingredient is fexofenadine hydrochloride 120mg per tablet.
Excipients (inactive ingredients)
- Microcrystalline cellulose — binder and filler providing tablet structural integrity
- Pregelatinised starch — binder and disintegrant
- Croscarmellose sodium — disintegrant promoting tablet dissolution and active ingredient release
- Magnesium stearate — lubricant used in manufacture
- Hypromellose — film-coating agent
- Povidone — binder ensuring uniform active ingredient distribution
- Titanium dioxide — white colouring agent in film coat
- Iron oxide yellow and iron oxide red — colouring agents giving the tablet its characteristic peach appearance
- Macrogol 400 — plasticiser in the film coating
If you have a known sensitivity to any ingredient, speak to a Pearl Chemist Group pharmacist before use.
Last reviewed: May 2026.
Always read the patient information leaflet before use. A copy is included in the pack. For advice, speak to a Pearl Chemist pharmacist or call +44 (0)20 8672 2157.
What Are Allevia Fexofenadine 120mg Tablets Used For?
Hayfever is one of the most prevalent allergic conditions in the United Kingdom, affecting an estimated 13 million people and causing significant disruption to daily life, sleep, productivity, and wellbeing during the spring and summer pollen seasons. Sneezing, a relentlessly runny nose, itchy and streaming eyes, and an itchy throat and palate — often accompanied by fatigue from disrupted sleep — are all symptoms that many people endure for months each year. Allevia Fexofenadine Hydrochloride Tablets 120mg offer effective once-daily relief from these symptoms of seasonal allergic rhinitis without the drowsiness that limits the usefulness of many older antihistamine preparations. The 15-tablet pack is a convenient standard-sized supply for the hayfever season.
The active ingredient is fexofenadine hydrochloride at 120mg per tablet. Fexofenadine is a potent, highly selective, non-sedating antihistamine that works by competitively blocking histamine H1 receptors in the nasal mucosa, eyes, throat, and skin. When pollen or another seasonal allergen triggers an immune response in susceptible individuals, mast cells release histamine, which binds to H1 receptors and produces the characteristic symptoms of hayfever. Fexofenadine prevents this binding, blocking the histamine-driven cascade that causes sneezing, nasal secretion, itching, and eye irritation. A single 120mg dose provides sustained H1 receptor blockade for a full 24 hours, allowing once-daily dosing that fits easily into a morning routine and provides consistent, reliable coverage throughout the day and evening.
What sets fexofenadine apart from many other antihistamines available for hayfever is its particularly strong non-sedating profile. Unlike first-generation antihistamines and even some second-generation options, fexofenadine does not cross the blood-brain barrier to any clinically significant degree at therapeutic doses. This means it provides effective symptom relief without causing the drowsiness, impaired concentration, or reduced reaction time that can significantly affect driving safety and workplace performance. Clinical trials have shown its sedation rate to be statistically indistinguishable from placebo.
There is one important practical instruction that applies specifically to fexofenadine and has a meaningful impact on its effectiveness: it must always be taken with water, never with fruit juice. Grapefruit juice, orange juice, and apple juice all significantly reduce fexofenadine absorption and should be avoided around the time the tablet is taken. Allevia 120mg is suitable for adults and young people aged 12 and over, and is available as a General Sale medicine (GSL). Speak to a Pearl Chemist Group pharmacist for personalised hayfever management advice, or browse our full hayfever and allergy range.
How to Use Allevia Fexofenadine 120mg Tablets
- Take one tablet once daily. Remove one tablet from the blister and take it before a meal, at the same time each day.
- Always take with a full glass of plain water. Never take with fruit juice of any kind — grapefruit, orange, and apple juices all significantly reduce fexofenadine absorption. Plain water is the only suitable drink for taking this tablet.
- Swallow whole. Do not crush or chew the tablet.
- Take at the same time each day. Consistent daily dosing maintains effective, sustained antihistamine coverage and provides the best symptom control throughout the day and overnight.
- If you take antacids, time your doses carefully. Leave at least 2 hours between fexofenadine and any antacid containing aluminium or magnesium hydroxide.
Tips for best results during hayfever season
- Starting fexofenadine a few days before your hayfever season typically begins can help to establish effective coverage before symptoms peak.
- If you also suffer from eye symptoms, your pharmacist may recommend combining fexofenadine with an antihistamine eye drop for additional ocular relief.
- For those with significant nasal congestion that oral antihistamines alone do not fully address, a topical corticosteroid nasal spray used alongside daily fexofenadine often provides substantially better overall hayfever control.
Allevia Fexofenadine 120mg Tablets Side Effects
Fexofenadine is very well tolerated with a side effect profile closely comparable to placebo in clinical trials.
Common side effects (may affect more than 1 in 10 people)
- Headache
- Drowsiness — incidence is very low and comparable to placebo in clinical trials
Less common side effects (may affect between 1 in 10 and 1 in 100 people)
- Nausea or stomach upset
- Dizziness
- Fatigue
- Dry mouth
Rare side effects (may affect fewer than 1 in 100 people)
- Sleep disturbance
- Rapid or irregular heartbeat
- Skin rash or hypersensitivity reactions
Stop using and seek medical help if you experience:
- Rapid or irregular heartbeat that is new or persistent
- Signs of a serious allergic reaction — call 999 immediately
Report any unexpected reaction via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk or speak to your Pearl Chemist Group pharmacist.
How to Store Allevia Fexofenadine 120mg Tablets 15 Pack
- Temperature: Store below 30°C. Keep away from direct sunlight and heat sources.
- Packaging: Keep in the original blister pack inside the outer carton.
- Do not refrigerate.
- Children: Keep out of the sight and reach of children.
- Expiry: Do not use after the expiry date on the blister and outer packaging.
- Disposal: Return unused tablets to your Pearl Chemist Group pharmacy for safe disposal.
Who Are Allevia Fexofenadine 120mg Tablets Suitable For?
Allevia Fexofenadine Hydrochloride Tablets 120mg are suitable for adults and young people aged 12 and over who experience symptoms of seasonal allergic rhinitis (hayfever) and require effective, once-daily, non-sedating antihistamine relief.
Suitable for:
- Adults with sneezing, runny nose, nasal congestion, itchy and watery eyes, and itchy nose and throat caused by seasonal hayfever
- Young people aged 12 to 17, subject to appropriate adult supervision
- Those who need to drive, operate machinery, or maintain full alertness during hayfever treatment
- People who have found other antihistamines too sedating for daytime use
- Those who prefer a once-daily tablet for simplicity and consistent coverage
- People who experience hayfever symptoms across a substantial part of the pollen season and prefer a standard supply pack
Not suitable for:
- Children under 12 years of age
- Anyone with known hypersensitivity to fexofenadine hydrochloride, hydroxyzine, or any excipient
- Those with severe renal impairment without prior medical guidance
- Use for chronic idiopathic urticaria (hives) — the specifically licensed dose for urticaria is 180mg, not 120mg
Use with caution or seek advice first if you:
- Have any degree of renal impairment
- Are pregnant or breastfeeding
- Take antacids containing aluminium or magnesium hydroxide — separate doses by at least 2 hours
- Regularly consume large quantities of fruit juice with morning medicines
Our Pearl Chemist Group pharmacists are available for personalised hayfever management advice.
Active Ingredients in Allevia Fexofenadine 120mg Tablets
| Ingredient | Strength per tablet | Role |
|---|---|---|
| Fexofenadine hydrochloride | 120mg | A potent, highly selective, non-sedating antihistamine. Fexofenadine blocks peripheral histamine H1 receptors, preventing histamine — released in response to pollen and other seasonal allergens — from triggering the nasal, ocular, and throat symptoms of hayfever. A single 120mg dose provides 24-hour coverage, making once-daily dosing sufficient for consistent allergy control. Fexofenadine does not cross the blood-brain barrier to any clinically significant extent at this dose, which is the basis for its non-sedating, non-impairing profile that allows normal driving and workplace performance during treatment. |
Allevia Fexofenadine 120mg Tablets Dosage — How Much to Take
Adults and young people aged 12 and over
- Dose: 120mg (1 tablet) once daily.
- When to take: Before a meal, at the same time each day. Take with a full glass of water — never with fruit juice.
- Duration: Use throughout the hayfever season or as long as symptoms are present. Starting a few days before the expected onset of the pollen season may help to establish protective H1 receptor blockade before symptoms develop.
Children under 12 years
Not recommended.
Elderly patients
No dose adjustment is required in elderly patients with normal renal function. In those with impaired kidney function, consult your pharmacist or GP.
Critical instructions — fexofenadine absorption
- Always take with water — fruit juices significantly reduce absorption.
- Take before food for optimal absorption.
- Separate from antacid doses (aluminium or magnesium hydroxide-based) by at least 2 hours.
Precautions When Using Allevia Fexofenadine 120mg Tablets
Before use
- Check the expiry date on the blister and outer packaging.
- Confirm no hypersensitivity to fexofenadine or hydroxyzine.
- If you have renal impairment, seek pharmacist or GP guidance before use.
- Do not use during pregnancy or breastfeeding without medical guidance.
During use
- Always take with water, never with fruit juice.
- Take before food for best absorption.
- Separate doses from antacids by at least 2 hours.
- Take at the same time every day.
When to seek medical advice
- Hayfever symptoms are not adequately controlled despite consistent daily treatment.
- You develop new symptoms or your condition changes significantly.
- You experience any side effect that concerns you.
Our Pearl Chemist Group pharmacists can advise on comprehensive hayfever management strategies.
Full Ingredients in Allevia Fexofenadine 120mg Tablets
The active ingredient is fexofenadine hydrochloride 120mg per tablet.
Excipients (inactive ingredients)
- Microcrystalline cellulose — binder and filler providing tablet structural integrity
- Pregelatinised starch — binder and disintegrant
- Croscarmellose sodium — disintegrant promoting tablet dissolution and active ingredient release
- Magnesium stearate — lubricant used in manufacture
- Hypromellose — film-coating agent
- Povidone — binder ensuring uniform active ingredient distribution
- Titanium dioxide — white colouring agent in film coat
- Iron oxide yellow and iron oxide red — colouring agents giving the tablet its characteristic peach appearance
- Macrogol 400 — plasticiser in the film coating
If you have a known sensitivity to any ingredient, speak to a Pearl Chemist Group pharmacist before use.
Last reviewed: May 2026.
Always read the patient information leaflet before use. A copy is included in the pack. For advice, speak to a Pearl Chemist pharmacist or call +44 (0)20 8672 2157.
FAQs
All three are second-generation antihistamines and provide effective once-daily hayfever relief, but fexofenadine has the most favourable non-sedating profile of the group. Clinical trials consistently show its drowsiness rate to be statistically indistinguishable from placebo, which is not always the case for cetirizine (which can cause mild drowsiness in a proportion of users) and loratadine (which is considered non-sedating but carries a small sedation risk). For people who drive professionally, operate machinery, or are particularly sensitive to even mild antihistamine sedation, fexofenadine is often the preferred choice.
Grapefruit juice, orange juice, and apple juice all significantly reduce the absorption of fexofenadine by inhibiting the intestinal transport proteins that carry the drug from the gut into the bloodstream. Studies have demonstrated that apple juice, for example, can reduce fexofenadine bioavailability by more than a third. This means that taking your Allevia tablet with a glass of orange juice at breakfast could substantially reduce how much active drug reaches your bloodstream, making the tablet considerably less effective than it should be. This is one of the most clinically important aspects of taking fexofenadine correctly — always use plain water.
Yes. Allevia 120mg is suitable for daily use throughout the hayfever season. For those with predictable seasonal symptoms, starting the tablet a few days before the pollen season begins can help to establish effective H1 receptor blockade before symptoms develop. Continue taking it every day until the season ends and symptoms resolve. The 15-tablet pack provides a standard two-week supply; for the full hayfever season, the 30-tablet pack offers better economy and reduces the frequency of repurchasing.
No. Allevia 120mg is specifically licensed for seasonal allergic rhinitis (hayfever). For chronic idiopathic urticaria (hives), the licensed dose of fexofenadine is 180mg, not 120mg. Allevia Hives 180mg is the appropriate product for urticaria management, and it is available as a Pharmacy (P) medicine from Pearl Chemist Group. If you are unsure which product is right for your symptoms, speak to a Pearl Chemist Group pharmacist.
Fexofenadine is effective for the histamine-driven symptoms of hayfever — sneezing, runny nose, itchy and watery eyes, and itchy nose and throat. Nasal congestion has a more complex pathophysiology that is less purely histamine-mediated, so oral antihistamines alone, including fexofenadine, may not provide complete relief for significant nasal congestion. For those whose congestion is a predominant symptom, combining fexofenadine with a topical nasal corticosteroid spray provides much better overall symptom control. Speak to a Pearl Chemist Group pharmacist about the best combination for your specific symptom profile.
The main dietary interaction to be aware of is fruit juice — grapefruit, orange, and apple juice should all be avoided around the time you take your fexofenadine tablet. Beyond this, there are no specific food restrictions. Fexofenadine is not affected by alcohol in the way that sedating antihistamines are, though responsible alcohol consumption guidance applies as normal.
Fexofenadine is not recommended during pregnancy because there are insufficient human safety data to confirm it is safe across all trimesters. If you are pregnant and suffering from significant hayfever symptoms, consult your GP or midwife who can advise on the most appropriate management option for your stage of pregnancy, taking into account both symptom severity and available safety evidence for any proposed treatment.