Amoxicillin Capsules 500mg – 21 Capsules

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What Are Amoxicillin Capsules 500mg Used For?
Amoxicillin Capsules 500mg are a prescription antibiotic used to treat a range of bacterial infections in adults and children. Amoxicillin belongs to the penicillin class of antibiotics and has been used for decades as one of the most widely prescribed and well-studied antibacterial medicines available. If you have been prescribed amoxicillin, your doctor has assessed that you have a bacterial infection that requires antibiotic treatment — it is important to take the full prescribed course as directed, even if you begin to feel better before the course is complete.
Amoxicillin works by inhibiting the synthesis of bacterial cell walls. It binds to penicillin-binding proteins (PBPs) on the bacterial cell membrane, blocking the cross-linking of peptidoglycan chains that give the bacterial cell wall its structural integrity. Without a functioning cell wall, bacteria cannot maintain their internal osmotic pressure, leading to cell lysis and death. Amoxicillin is effective against a broad range of gram-positive and some gram-negative bacteria, making it appropriate for a wide range of common infections in both community and clinical settings.
Common conditions for which amoxicillin is prescribed include upper and lower respiratory tract infections such as tonsillitis, sinusitis, otitis media (middle ear infection), bronchitis, and community-acquired pneumonia; urinary tract infections; skin and soft tissue infections; and dental infections. The specific indication, dose, and duration of your course will have been determined by your prescriber based on the type and severity of your infection.
It is important to complete the full course of amoxicillin as prescribed, even if your symptoms improve significantly before all capsules are taken. Stopping antibiotic treatment early risks leaving a residual bacterial population that may allow the infection to return, potentially with reduced antibiotic sensitivity. If you have any questions about your prescription, speak to a Pearl Chemist Group pharmacist who can provide guidance on how to take your medicine correctly.
This medicine requires a prescription from a registered UK prescriber. It cannot be purchased over the counter.
How to Take Amoxicillin Capsules 500mg
- Take as directed on your prescription label. Follow the exact dose, frequency, and duration written on your prescription and confirmed by your pharmacist.
- Swallow capsules whole with water. Swallow each capsule with a full glass of water. Amoxicillin capsules may be taken with or without food — food does not significantly affect absorption.
- Take at regular intervals throughout the day. If your prescription specifies three times daily, space doses evenly — for example, morning, midday, and evening — to maintain consistent blood levels of the antibiotic throughout the day.
- If you miss a dose. Take the missed dose as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue as normal. Do not double up doses.
- Complete the full course. Take all capsules in the pack as prescribed, even if you feel fully recovered before the course ends.
Practical tips
- If you experience stomach upset, taking capsules with a light meal or snack may help.
- Store any unused capsules as directed and return them to your pharmacy if you have remaining capsules after the course is complete.
- Do not share antibiotics with other people, even if their symptoms appear similar to yours.
Amoxicillin Capsules 500mg Side Effects
Like all antibiotics, amoxicillin can cause side effects, though not everybody experiences them.
Common side effects (may affect more than 1 in 10 people)
- Diarrhoea — the most common side effect; usually mild and resolves after completing the course
- Nausea — taking capsules with food can help to reduce this
- Skin rash — a mild, non-allergic rash can occur with amoxicillin; if the rash is widespread, severe, or accompanied by other symptoms, seek medical advice
Less common side effects (may affect between 1 in 10 and 1 in 100 people)
- Vomiting
- Indigestion
- Thrush (oral or vaginal candidiasis) — antibiotics can disrupt the normal bacterial flora, allowing Candida to overgrow; speak to your pharmacist about appropriate treatment if this occurs
Rare side effects (may affect fewer than 1 in 100 people)
- Antibiotic-associated colitis, including Clostridioides difficile infection — presenting as severe, prolonged, or bloody diarrhoea during or after the course; seek urgent medical advice if this occurs
- Liver enzyme changes or jaundice
- Blood disorders
Stop taking and seek urgent medical help if you experience:
- Signs of anaphylaxis — throat swelling, difficulty breathing, widespread urticaria, or collapse — call 999 immediately
- Severe, persistent, or bloody diarrhoea during or after the course
- Jaundice (yellowing of the skin or eyes)
- Severe skin reactions including blistering
Report any unexpected reaction via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk or speak to your Pearl Chemist Group pharmacist.
How to Store Amoxicillin Capsules 500mg
- Temperature: Store below 25°C. Keep away from direct sunlight and sources of heat and moisture.
- Packaging: Keep in the original packaging until use.
- Children: Keep out of the sight and reach of children at all times.
- Expiry: Do not use after the expiry date printed on the packaging.
- Unused capsules: Return any remaining capsules at the end of your course to your Pearl Chemist Group pharmacy for safe disposal. Do not dispose of via wastewater or household waste.
Who Are Amoxicillin Capsules 500mg Prescribed For?
Amoxicillin Capsules 500mg are prescribed for adults and children with confirmed or clinically assessed bacterial infections requiring a penicillin-class antibiotic. Prescribing decisions are made by a qualified healthcare professional.
Common prescribing indications include:
- Upper respiratory tract infections — tonsillitis, sinusitis, otitis media (middle ear infection)
- Lower respiratory tract infections — acute bronchitis, community-acquired pneumonia
- Urinary tract infections — cystitis and uncomplicated UTIs
- Skin and soft tissue infections
- Dental infections and dental abscesses
- Other bacterial infections as determined by the prescriber
This medicine is not appropriate for:
- Viral infections — amoxicillin will not treat colds, influenza, or other viral illnesses; taking antibiotics for viral infections is ineffective and contributes to antibiotic resistance
- Those with a known penicillin allergy — amoxicillin is a penicillin antibiotic and must not be used in penicillin-allergic individuals
- Those with a history of severe hypersensitivity (anaphylaxis) to penicillins or cephalosporins
- Those with infectious mononucleosis (glandular fever) — amoxicillin almost always causes a widespread skin rash in this condition
If you have any concerns about your prescription or whether amoxicillin is appropriate for you, speak to your prescriber or to a Pearl Chemist Group pharmacist.
Active Ingredients in Amoxicillin Capsules 500mg
| Ingredient | Strength per capsule | Role |
|---|---|---|
| Amoxicillin (as amoxicillin trihydrate) | 500mg | A broad-spectrum penicillin-class antibiotic. Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), disrupting peptidoglycan cross-linking and causing bacterial cell lysis. It is bactericidal (kills bacteria) and effective against a range of gram-positive and gram-negative organisms commonly responsible for respiratory, urinary, skin, and dental infections. The 500mg capsule provides the standard adult therapeutic dose for most community-acquired bacterial infections. |
Amoxicillin Capsules 500mg Dosage — How Much to Take
Always follow your prescriber's instructions exactly. The dose, frequency, and duration of your amoxicillin course will depend on the type and severity of your infection. The following are typical adult dosage guidelines, but your individual prescription may differ.
Adults (typical doses)
- Standard dose: 250–500mg three times daily.
- Higher dose for severe infections: 500mg three times daily or as prescribed.
- Duration: Typically 5–7 days for most infections; longer courses may be prescribed for more complex infections such as pneumonia or dental abscesses.
Children
Dosing in children is weight-based and will be specified on the prescription label. For children, oral liquid formulations are often more appropriate than capsules.
Renal impairment
Dose adjustment may be required in those with significant renal impairment. Your prescriber will have taken this into account. If you have kidney disease and have any concerns about your dose, consult your GP or pharmacist.
Critical — complete the full course
Complete every capsule in the prescribed course even if you feel better. Stopping early risks treatment failure and contributes to antibiotic resistance.
Precautions When Taking Amoxicillin Capsules 500mg
- Always inform your prescriber and pharmacist of any known antibiotic allergy before starting treatment.
- Complete the full prescribed course — do not stop early even if symptoms resolve.
- Do not share your antibiotics with other people.
- Do not take antibiotics prescribed for a previous illness or that belong to someone else.
- Store as directed and return unused capsules to your pharmacy for safe disposal — do not dispose of via wastewater or household waste.
- If you develop a widespread skin rash during treatment, contact your GP or prescriber, as this may indicate an allergic reaction or, if glandular fever was not previously excluded, an amoxicillin-induced rash.
If you have any questions about your prescription, speak to a Pearl Chemist Group pharmacist who can provide personalised guidance on taking your medicine safely and correctly.
Full Ingredients in Amoxicillin Capsules 500mg
The active ingredient is amoxicillin 500mg per capsule (as amoxicillin trihydrate).
Excipients (inactive ingredients)
- Magnesium stearate — lubricant used in capsule manufacture to ensure consistent filling and prevent content from sticking
- Gelatin capsule shell — the hard gelatin capsule that contains the active ingredient; those with a known gelatin allergy or religious/dietary objections to gelatin should discuss alternative formulations with their prescriber or pharmacist
If you have a known sensitivity to any ingredient, inform your prescriber and pharmacist before taking this medicine.
Last reviewed: May 2026.
Always read the patient information leaflet before use. A copy is included in the pack. For advice, speak to a Pearl Chemist pharmacist or call +44 (0)20 8672 2157.
What Are Amoxicillin Capsules 500mg Used For?
Amoxicillin Capsules 500mg are a prescription antibiotic used to treat a range of bacterial infections in adults and children. Amoxicillin belongs to the penicillin class of antibiotics and has been used for decades as one of the most widely prescribed and well-studied antibacterial medicines available. If you have been prescribed amoxicillin, your doctor has assessed that you have a bacterial infection that requires antibiotic treatment — it is important to take the full prescribed course as directed, even if you begin to feel better before the course is complete.
Amoxicillin works by inhibiting the synthesis of bacterial cell walls. It binds to penicillin-binding proteins (PBPs) on the bacterial cell membrane, blocking the cross-linking of peptidoglycan chains that give the bacterial cell wall its structural integrity. Without a functioning cell wall, bacteria cannot maintain their internal osmotic pressure, leading to cell lysis and death. Amoxicillin is effective against a broad range of gram-positive and some gram-negative bacteria, making it appropriate for a wide range of common infections in both community and clinical settings.
Common conditions for which amoxicillin is prescribed include upper and lower respiratory tract infections such as tonsillitis, sinusitis, otitis media (middle ear infection), bronchitis, and community-acquired pneumonia; urinary tract infections; skin and soft tissue infections; and dental infections. The specific indication, dose, and duration of your course will have been determined by your prescriber based on the type and severity of your infection.
It is important to complete the full course of amoxicillin as prescribed, even if your symptoms improve significantly before all capsules are taken. Stopping antibiotic treatment early risks leaving a residual bacterial population that may allow the infection to return, potentially with reduced antibiotic sensitivity. If you have any questions about your prescription, speak to a Pearl Chemist Group pharmacist who can provide guidance on how to take your medicine correctly.
This medicine requires a prescription from a registered UK prescriber. It cannot be purchased over the counter.
How to Take Amoxicillin Capsules 500mg
- Take as directed on your prescription label. Follow the exact dose, frequency, and duration written on your prescription and confirmed by your pharmacist.
- Swallow capsules whole with water. Swallow each capsule with a full glass of water. Amoxicillin capsules may be taken with or without food — food does not significantly affect absorption.
- Take at regular intervals throughout the day. If your prescription specifies three times daily, space doses evenly — for example, morning, midday, and evening — to maintain consistent blood levels of the antibiotic throughout the day.
- If you miss a dose. Take the missed dose as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue as normal. Do not double up doses.
- Complete the full course. Take all capsules in the pack as prescribed, even if you feel fully recovered before the course ends.
Practical tips
- If you experience stomach upset, taking capsules with a light meal or snack may help.
- Store any unused capsules as directed and return them to your pharmacy if you have remaining capsules after the course is complete.
- Do not share antibiotics with other people, even if their symptoms appear similar to yours.
Amoxicillin Capsules 500mg Side Effects
Like all antibiotics, amoxicillin can cause side effects, though not everybody experiences them.
Common side effects (may affect more than 1 in 10 people)
- Diarrhoea — the most common side effect; usually mild and resolves after completing the course
- Nausea — taking capsules with food can help to reduce this
- Skin rash — a mild, non-allergic rash can occur with amoxicillin; if the rash is widespread, severe, or accompanied by other symptoms, seek medical advice
Less common side effects (may affect between 1 in 10 and 1 in 100 people)
- Vomiting
- Indigestion
- Thrush (oral or vaginal candidiasis) — antibiotics can disrupt the normal bacterial flora, allowing Candida to overgrow; speak to your pharmacist about appropriate treatment if this occurs
Rare side effects (may affect fewer than 1 in 100 people)
- Antibiotic-associated colitis, including Clostridioides difficile infection — presenting as severe, prolonged, or bloody diarrhoea during or after the course; seek urgent medical advice if this occurs
- Liver enzyme changes or jaundice
- Blood disorders
Stop taking and seek urgent medical help if you experience:
- Signs of anaphylaxis — throat swelling, difficulty breathing, widespread urticaria, or collapse — call 999 immediately
- Severe, persistent, or bloody diarrhoea during or after the course
- Jaundice (yellowing of the skin or eyes)
- Severe skin reactions including blistering
Report any unexpected reaction via the MHRA Yellow Card scheme at yellowcard.mhra.gov.uk or speak to your Pearl Chemist Group pharmacist.
How to Store Amoxicillin Capsules 500mg
- Temperature: Store below 25°C. Keep away from direct sunlight and sources of heat and moisture.
- Packaging: Keep in the original packaging until use.
- Children: Keep out of the sight and reach of children at all times.
- Expiry: Do not use after the expiry date printed on the packaging.
- Unused capsules: Return any remaining capsules at the end of your course to your Pearl Chemist Group pharmacy for safe disposal. Do not dispose of via wastewater or household waste.
Who Are Amoxicillin Capsules 500mg Prescribed For?
Amoxicillin Capsules 500mg are prescribed for adults and children with confirmed or clinically assessed bacterial infections requiring a penicillin-class antibiotic. Prescribing decisions are made by a qualified healthcare professional.
Common prescribing indications include:
- Upper respiratory tract infections — tonsillitis, sinusitis, otitis media (middle ear infection)
- Lower respiratory tract infections — acute bronchitis, community-acquired pneumonia
- Urinary tract infections — cystitis and uncomplicated UTIs
- Skin and soft tissue infections
- Dental infections and dental abscesses
- Other bacterial infections as determined by the prescriber
This medicine is not appropriate for:
- Viral infections — amoxicillin will not treat colds, influenza, or other viral illnesses; taking antibiotics for viral infections is ineffective and contributes to antibiotic resistance
- Those with a known penicillin allergy — amoxicillin is a penicillin antibiotic and must not be used in penicillin-allergic individuals
- Those with a history of severe hypersensitivity (anaphylaxis) to penicillins or cephalosporins
- Those with infectious mononucleosis (glandular fever) — amoxicillin almost always causes a widespread skin rash in this condition
If you have any concerns about your prescription or whether amoxicillin is appropriate for you, speak to your prescriber or to a Pearl Chemist Group pharmacist.
Active Ingredients in Amoxicillin Capsules 500mg
| Ingredient | Strength per capsule | Role |
|---|---|---|
| Amoxicillin (as amoxicillin trihydrate) | 500mg | A broad-spectrum penicillin-class antibiotic. Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), disrupting peptidoglycan cross-linking and causing bacterial cell lysis. It is bactericidal (kills bacteria) and effective against a range of gram-positive and gram-negative organisms commonly responsible for respiratory, urinary, skin, and dental infections. The 500mg capsule provides the standard adult therapeutic dose for most community-acquired bacterial infections. |
Amoxicillin Capsules 500mg Dosage — How Much to Take
Always follow your prescriber's instructions exactly. The dose, frequency, and duration of your amoxicillin course will depend on the type and severity of your infection. The following are typical adult dosage guidelines, but your individual prescription may differ.
Adults (typical doses)
- Standard dose: 250–500mg three times daily.
- Higher dose for severe infections: 500mg three times daily or as prescribed.
- Duration: Typically 5–7 days for most infections; longer courses may be prescribed for more complex infections such as pneumonia or dental abscesses.
Children
Dosing in children is weight-based and will be specified on the prescription label. For children, oral liquid formulations are often more appropriate than capsules.
Renal impairment
Dose adjustment may be required in those with significant renal impairment. Your prescriber will have taken this into account. If you have kidney disease and have any concerns about your dose, consult your GP or pharmacist.
Critical — complete the full course
Complete every capsule in the prescribed course even if you feel better. Stopping early risks treatment failure and contributes to antibiotic resistance.
Precautions When Taking Amoxicillin Capsules 500mg
- Always inform your prescriber and pharmacist of any known antibiotic allergy before starting treatment.
- Complete the full prescribed course — do not stop early even if symptoms resolve.
- Do not share your antibiotics with other people.
- Do not take antibiotics prescribed for a previous illness or that belong to someone else.
- Store as directed and return unused capsules to your pharmacy for safe disposal — do not dispose of via wastewater or household waste.
- If you develop a widespread skin rash during treatment, contact your GP or prescriber, as this may indicate an allergic reaction or, if glandular fever was not previously excluded, an amoxicillin-induced rash.
If you have any questions about your prescription, speak to a Pearl Chemist Group pharmacist who can provide personalised guidance on taking your medicine safely and correctly.
Full Ingredients in Amoxicillin Capsules 500mg
The active ingredient is amoxicillin 500mg per capsule (as amoxicillin trihydrate).
Excipients (inactive ingredients)
- Magnesium stearate — lubricant used in capsule manufacture to ensure consistent filling and prevent content from sticking
- Gelatin capsule shell — the hard gelatin capsule that contains the active ingredient; those with a known gelatin allergy or religious/dietary objections to gelatin should discuss alternative formulations with their prescriber or pharmacist
If you have a known sensitivity to any ingredient, inform your prescriber and pharmacist before taking this medicine.
Last reviewed: May 2026.
Always read the patient information leaflet before use. A copy is included in the pack. For advice, speak to a Pearl Chemist pharmacist or call +44 (0)20 8672 2157.
FAQs
Completing the full antibiotic course is essential for two reasons. First, stopping early means the bacteria causing your infection may not be fully eradicated — residual bacteria can cause the infection to return, often with greater severity. Second, any surviving bacteria may be those that were naturally slightly more resistant to the antibiotic, and allowing them to multiply contributes to the development of antibiotic-resistant strains — a significant public health problem. Always complete every capsule in your prescribed course, even if you feel much better before it is finished.
No. Colds and influenza are caused by viruses, and amoxicillin — like all antibiotics — is only effective against bacteria. Taking antibiotics for viral infections provides no therapeutic benefit and contributes to antibiotic resistance. Your prescriber will only prescribe amoxicillin when a bacterial infection has been clinically assessed. If you have a cold or flu, rest, hydration, and appropriate symptomatic relief from over-the-counter medicines are the recommended management approach.
If you have ever had a reaction to penicillin or amoxicillin — including a rash, hives, swelling, or breathing difficulty — this must be reported to your prescriber and pharmacist before starting any new course. Do not take amoxicillin if you have a known penicillin allergy. True penicillin allergy means an alternative antibiotic class will need to be prescribed. If you are unsure whether your previous reaction was truly an allergy, speak to your GP, as formal allergy assessment can clarify this — many people labelled as penicillin-allergic are later found not to be, which has significant implications for their future antibiotic treatment options.
Unlike some antibiotics such as metronidazole, amoxicillin does not have a significant direct pharmacological interaction with alcohol. Moderate alcohol consumption is unlikely to reduce the effectiveness of amoxicillin or cause a direct adverse reaction. However, alcohol can impair immune function and may exacerbate the nausea and gastrointestinal side effects that some people experience with antibiotics. Avoiding or limiting alcohol during the treatment course is sensible advice while your body is fighting an infection.
Current UK guidance from the Faculty of Sexual and Reproductive Healthcare (FSRH) does not recommend additional contraceptive precautions for women taking most antibiotics alongside combined hormonal contraceptives, as there is no robust evidence that broad-spectrum antibiotics reduce contraceptive efficacy. However, if the diarrhoea or vomiting caused by amoxicillin is severe enough to interfere with pill absorption, additional barrier contraception should be used until normal pill absorption is restored. Speak to your Pearl Chemist Group pharmacist for the most current guidance on contraception during antibiotic treatment.
Mild diarrhoea is a common side effect of amoxicillin and usually resolves after completing the course as the gut flora rebalances. Keep well hydrated and continue the course. However, if the diarrhoea is severe, persistent (lasting more than 24 to 48 hours after finishing the course), bloody, or accompanied by significant abdominal pain and fever, seek urgent medical advice. Severe antibiotic-associated diarrhoea can sometimes be caused by Clostridioides difficile infection, a serious condition that requires specific treatment.